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Product introduction

Topotecan (SKF 104864; NSC 609669) 是一种口服有效的拓扑异构酶 I (Topoisomerase I) 抑制剂。Topotecan 诱导细胞周期阻滞在 G0/G1 和 S 期，促进凋亡 (apoptosis)。Topotecan 具有抗癌活性。 Information Topotecan is an antineoplastic agent used to treat ovarian cancer that works by inhibitingDNA topoisomerases. Targets Topo I

Specs ⸢ View details ⸥

Chinese name

Topotecan, DNA 拓扑异构酶 I 线粒体抑制剂

English name

Topotecan

Chinese alias

拓扑替康 | 托泊替康 | 拓扑替康

English alias

(s)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)-quinoline-3,14(4H,12H)-dione | (S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione | BP-29353 | B

CAS number

123948-87-8

molecular formula

C23H23N3O5

molecular weight

421.45 g/mol

Exact mass

PSA

103.000 Å²

Logp

0.5

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