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Product introduction

CCT018159 是一种 3,4-二芳基吡唑间苯二酚，一种 ATP 竞争性 HSP90 ATPase 活性抑制剂，对人 Hsp90β 和酵母 Hsp90 的 IC50 分别为 3.2 和 6.6 µM。CCT018159 引起与 G1 期阻滞相关的细胞细胞抑制并诱导细胞凋亡。CCT018159 抑制与侵袭和血管生成有关的关键内皮细胞和肿瘤细胞功能。 CCT018159, a 3,4-diaryl pyrazoleresorcinol, is a ATP-competitive HSP90 ATPase activity inhibitor with IC50s of 3.2 and 6.6 µM for human Hsp90β and yeast Hsp90, respectively. CCT018159 caused cell cytostasis associated with a G1 arrest and induces apoptosis. CCT018159 inhibits key endothelial and tumor cell functions implicated in invasion and angiogenesis。

Specs ⸢ View details ⸥

Chinese name

CCT 018159,,Hsp90 ATPase抑制剂

English name

CCT 018159

Chinese alias

4-[4-(2,3-二氢-1,4-苯并二恶英-6-基)-5-甲基-1H-吡唑-3-基]-6-乙基-1,3-苯二醇

English alias

Q27164868 | BDBM15362 | 4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethylbenzene-1,3-diol | 6-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxy-1-cyclohexa-2,4-dienone | 4-(4-(2,3-dihydr

CAS number

171009-07-7

molecular formula

C20H20N2O4

molecular weight

352.38 g/mol

Exact mass

≥98%

PSA

87.600 Å²

Logp

3.700

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Research chemical CAS 171009-07-7 ≥98% 25mg

Name: Research chemical CAS 171009-07-7 ≥98% 25mg
Brand: 源叶
SKU: T48239-25mg

Yuanye Research chemical CAS 171009-07-7 ≥98% 25mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T48239-25mg

Product model：25mg

level： ≥98% 25mg

Lead Time：30days

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Research chemical CAS 171009-07-7 ≥98% 25mg

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