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Product introduction

CMPD101 是一种高效、高选择性、膜透性的 GRK2/3 小分子抑制剂，IC50 分别为 18 nM 和 5.4 nM。CMPD101 针对 GRK1、GRK5 ROCK-2 和 PKCα 的选择性较小，IC50 值分别为 3.1 μM，2.3 μM，1.4 μM 和 8.1 μM。CMPD101 可用于心衰疾病的研究。 product description： CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC50s of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, respectively. CMPD101 can be used for the study of heart failure。

Specs ⸢ View details ⸥

Chinese name

CMPD101,GRK2 / 3抑制剂, 肾上腺素能受体激酶 1 抑制剂

English name

CMPD101

Chinese alias

English alias

3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide | 3-(((4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)methyl)amino)-N-(2-(trifluoromethyl)benzyl)benzamide

CAS number

865608-11-3

molecular formula

C24H21F3N6O

molecular weight

466.46 g/mol

Exact mass

PSA

84.700 Å²

Logp

3.200

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Research chemical CAS 865608-11-3 ≥98% HPLC 5mg

Name: Research chemical CAS 865608-11-3 ≥98% HPLC 5mg
Brand: 源叶
SKU: T51522-5mg

Yuanye Research chemical CAS 865608-11-3 ≥98% HPLC 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T51522-5mg

Product model：5mg

level： ≥98% HPLC 5mg

Lead Time：30days

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Research chemical CAS 865608-11-3 ≥98% HPLC 5mg

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