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Product introduction

曲美苄胺是通过 3,4,5-三羟基苯甲酸与 4-[2-(N,N-二氨基)乙氧基]苄胺缩合形成的酰胺。用于预防人类恶心和呕吐。它具有止吐作用。它是苯甲酰胺类和三级氨基化合物的一员。

Specs ⸢ View details ⸥

Chinese name

Trimethobenzamide

English name

N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide

Chinese alias

三甲氧苯甲酰胺

English alias

CAS number

138-56-7

molecular formula

C21H28N2O5

molecular weight

388.5

Exact mass

PSA

69.3

Logp

2.3

Safety

Hepatotoxicity：可能性评分: D(可能是临床上明显的肝损伤的罕见原因)。

Special Reports：药理学。[BLESSEL 等人；药物物质分析图谱 2: 551 (1973)]

Human toxicity extract：服用盐酸曲美苄胺后发生肝炎。

Drug Induced Liver Injury：参考文献：DOI:10.1016/j.drudis.2019.09.022

Effects During Pregnancy and Lactation： ◉ 对哺乳和母乳的影响

Technical Documents

「No technical documents」

upstream information

Manufacturing method：

4-[2-(二甲基氨基)乙氧基]苄胺(CID:88349)；3,4,5-三甲氧基苯甲酰氯(CID:174940270)；三甲氧基苯甲酰胺(CID:249160)

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Consultation

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