
- Treatment: 如果化合物已被摄入,应使用5%碳酸氢钠进行快速洗胃。对于皮肤接触,应用肥皂和水清洗皮肤。如果化合物进入眼睛,应用大量等渗盐水或水冲洗。在严重情况下,应给予阿托品和/或吡啶肟肟。抗胆碱药物可对抗过量乙酰胆碱的作用并重新激活乙酰胆碱酯酶。阿托品可作为解毒剂与吡啶肟肟或其他吡啶肟肟类化合物(如三甲肟肟或肟肟肟)联合使用,但在至少两项荟萃分析中发现使用"-肟肟"类化合物没有益处,甚至可能有害。阿托品是毒蕈碱受体拮抗剂,因此在外周阻断乙酰胆碱的作用。
- Storage conditions: 储存...在控制室温下。...应避免冷冻。/氯化筒箭毒碱/
- Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
- exposure pathway: 注射(刺/叮)(L1256)
- Toxicity summary: 筒箭毒碱是胆碱酯酶或乙酰胆碱酯酶(AChE)抑制剂。胆碱酯酶抑制剂(或"抗胆碱酯酶")抑制乙酰胆碱酯酶的作用。由于其基本功能,干扰乙酰胆碱酯酶作用的化学品是强效神经毒素,低剂量时引起过量流涎和流泪,随后是肌肉痉挛,最终导致死亡。神经气体和许多用于杀虫剂的物质已被证明通过与乙酰胆碱酯酶活性位点的丝氨酸结合来发挥作用,完全抑制该酶。乙酰胆碱酯酶分解神经递质乙酰胆碱,乙酰胆碱在神经和肌肉接头处释放,以使肌肉或器官放松。乙酰胆碱酯酶抑制的结果...
- Health Effects: 胆碱酯酶抑制剂急性暴露可引起胆碱能危象,特征为严重恶心/呕吐、流涎、出汗、心动过缓、低血压、虚脱和惊厥。肌肉力量逐渐增强是可能的,如果呼吸肌受累,可能导致死亡。乙酰胆碱(ACh)在运动神经的积累会导致神经肌肉接头处烟碱受体的过度刺激。当发生这种情况时,可出现肌肉无力、疲劳、肌肉痉挛、肌束震颤和瘫痪等症状。当乙酰胆碱在自主神经节积累时,会导致交感神经系统烟碱受体的过度刺激。与此相关的症状是高血压和低血糖。中枢神经系统中烟碱乙酰胆碱受体的过度刺激...
- ecotoxicity value: 美国农业部动植物卫生检验局化学效应:collection=usda_chemeffect&query_type=synonym&query='^57-95-4$'
- Symptoms and Signs: 箭毒是一种肌肉松弛剂,因此会导致麻痹。(L1256)
- Human toxicity extract: 左肘窝意外动脉注射筒箭毒碱会导致肢体疼痛和无力。/氯化筒箭毒碱/
- Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
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tubocurarine 5mg
tubocurarine 5mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg.




