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Product introduction

TP0427736 hydrochloride is a potent inhibitor of ALK5 kinase activity with an IC 50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC 50 =836 nM). TP0427736 hydrochloride also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC 50 value of 8.68 nM. TP0427736 hydrochloride can be used for the research of androgenic alopecia (AGA). Form:Solid

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Chinese name

TP0427736 hydrochloride

English name

TP0427736 hydrochloride

Chinese alias

TP0427736 盐酸盐

English alias

CAS number

2459963-17-6

molecular formula

C14H11ClN4S2

molecular weight

334.9 g/mol

Exact mass

≥98%

PSA

111.000 Å²

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