Share to

Overview

Specs

Technical Documents

Articles

reviews

Consult

returns

Product introduction

TDP1 Inhibitor-2 (compound 5) is a potent inhibitor for TDP1 (tyrosyl-DNA phosphodiesterase 1), with an IC 50 of 99 nM. TDP1 Inhibitor-2 also can inhibit SCAN1 (spinocerebellar ataxia syndrome with axonal neuropathy), with an IC 50 of 3.5 μM In Vitro TDP1 Inhibitor-2 (compound 5) shows potent anti-TDP1 activity, low cytotoxicity and synergism with topotecan, an established Top1 anticancer agent. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC 50 : 0.099 ± 0.044 μM (TDP1), 3.5 ± 2.3 μM (SCAN1)

Specs ⸢ View details ⸥

Chinese name

TDP1 Inhibitor-2

English name

TDP1 Inhibitor-2

Chinese alias

TDP1 抑制剂-2

English alias

CAS number

859142-95-3

molecular formula

C25H14Cl2O5

molecular weight

465.28 g/mol

Exact mass

≥99%

PSA

Logp

Technical Documents

「No technical documents」

「No upstream and downstream information yet」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！