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Product introduction

Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim. In Vitro Trimethoprim 3-oxide is the primary metabolite of trimethoprim. Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates in human liver microsomes (HLMs). The CYP1A inhibitor α-Naphthoflavone inhibits Trimethoprim 3-oxide formation, however, other competitive P450 inhibitors has no obvious inhibition on the formation. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Specs ⸢ View details ⸥

Chinese name

Trimethoprim 3-oxide

English name

Trimethoprim 3-oxide

Chinese alias

甲氧苄啶 3-氧化物

English alias

CAS number

27653-67-4

molecular formula

C14H18N4O4

molecular weight

306.32 g/mol

Exact mass

PSA

113.000 Å²

Logp

0.4

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