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Product introduction

T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta ( PI4KB ) inhibitor with an IC 50 of 60 nM. In Vitro T-00127_HEV1 shows more potent anti-poliovirus (PV) activity (EC 50 of 0.77 μM) than other candidate compounds (EC 50 of 1.7 to 4.7 μM). GW5074 and T-00127_HEV1 almost completely inhibit PI4KB kinase activity at 10 μM (3% and 5% of residual activity, respectively), in contrast to AN-12-H5 (108% of activity [no inhibition]). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PI4KB 60 nM (IC 50 )

Specs ⸢ View details ⸥

Chinese name

T-00127_HEV1

English name

T-00127_HEV1

Chinese alias

English alias

CAS number

900874-91-1

molecular formula

C22H29N5O3

molecular weight

411.50 g/mol

Exact mass

≥99%

PSA

73.200 Å²

Logp

2.700

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