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名称

Tetrabenazine Racemate

别名

丁苯那嗪消旋体

英文名称

Tetrabenazine Racemate

货号

T654940-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

Tetrabenazine Racemate (Ro 1-9569 Racemate) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).(1) The reference for administration is 0.25-0.75 mg/kg IP (2) Injections of tetrabenazine into accumbens core also reduced FR5 lever pressing and increased chow intake.(3) Tetrabenazine (Racemate) reduced extracellular DA and altered DARPP-32 signaling in both substance-P- and enkephalin-containing accumbens neurons.(4) Tetrabenazine (Racemate) inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice.

生化机理

四苯嗪消旋物（Ro 1-9569 Racemate）是一种选择性和可逆性的囊泡单胺转运体-2（VMAT-2）抑制剂。

CAS号

718635-93-9(DMSO)

分子式

C19H27NO3

分子量

317.4 g/mol

Smiles

CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1=O)OC)OC

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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