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Product introduction

(8R,9S)-Talazoparib ((8R,9S)-BMN-673) is an enantiomer of Talazoparib. (8R,9S)-Talazoparib is an PARP1 inhibitor, with an IC 50 of 144 nM In Vitro (8R,9S)-Talazoparib shows an EC 50 of 864 nM in cellular PARylation assay. (8R,9S)-Talazoparib shows an EC 50 of 1135 nM for Capan-1 cells (BRCA2 mutant). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:PARP-1 144 nM (IC 50 )

Specs ⸢ View details ⸥

Chinese name

(8R,9S)-Talazoparib

English name

(8R,9S)-Talazoparib

Chinese alias

(8R,9S)-他拉唑帕尼

English alias

AC-30925 | NSC767533 | NSC-767533 | (8R,9S)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-1,2,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one | AKOS025405320 | HY-16106A | (8R,9S)-LT-673 | EX-A1355 | (8r,9s)-5-fluoro-8-(4-fluorophenyl)

CAS number

1207456-00-5

molecular formula

C19H14F2N6O

molecular weight

380.35 g/mol

Exact mass

≥98%

PSA

84.200 Å²

Logp

2.300

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