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Product details

名称

TP508 TFA

别名

TP508 三氟乙酸

英文名称

TP508 TFA

货号

T659453-5mg

包装规格

5mg

浓度

≥99%

储存温度

干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

TP508 TFA is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule. TP508 TFA activates endothelial NO synthase (eNOS) and stimulates production of NO in human endothelial cells. TP50 Appearance:Solid In Vitro:TP508 (50 μg/mL; 24 hours; HCAEC) treatment reverses radiation-induced endothelial dysfunction (ED) and loss of NO signaling by attenuating the downregulation of eNOS expression. TP508 treatment is able to stimulate NO production in the irradiated cells. In Vivo:TP508 (10mg/kg; intravenous injection; male CD-1 mice) treatment mitigates radiation-induced endothelial cell damage, also significantly increases survival of CD-1 mice when injected 24 h after 8.5 Gy exposure . MCE has not independently confirmed th Biological Activity:TP508 TFA is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule. TP508 TFA activates endothelial NO synthase (eNOS) and stimulates production of NO in human endothelial cells. TP50

分子式

C99H147N28F3O38S

分子量

2426.46 g/mol

溶解性

H2O : 50 mg/mL (20.61 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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