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Product introduction

7-Hydroxycoumarinyl arachidonate (7-HCA) 是胞质磷脂酶 A2 (PLA2) 的荧光底物，也是单酰基甘油脂肪酶 (MAGL) 的荧光底物。MAGL 蛋白催化 7-Hydroxycoumarinyl arachidonate 的水解，生成花生四烯酸 (AA；HY-109590) 和高荧光的 7-羟基香豆素 (7-HC；HY-N0573)，7-HC 的释放可以用荧光计进行测量。 7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer. Application： Umbelliferyl Arachidonate also known as 7-Hydroxycoumarinyl Arachidonate was used as a fluorogenic substrate for developing a fluorescence-based assay to evaluate the inhibitors against human recombinant monoacylglycerol lipase.

Specs ⸢ View details ⸥

Chinese name

(5Z,8Z,11Z,14Z)-5,8,11,14-二十碳四烯酸 2-氧代-2H-1-苯并吡喃-7-基酯

English name

7-HC-arachidonate

Chinese alias

7-羟基香豆素基花生四烯酸

English alias

Umbelliferyl Arachidonate | 5Z,8Z,11Z,14Z-Eicosatetraenoic acid 2-oxo-2H-1-benzopyran-7-yl ester | 7-Hydroxycoumarinyl Arachidonate | 7-HCA

CAS number

161180-11-6

molecular formula

C29H36O4

molecular weight

448.59 g/mol

Exact mass

≥95%

PSA

52.600 Å²

Logp

8.2

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Research chemical CAS 161180-11-6 95% 5mg

Name: Research chemical CAS 161180-11-6 95% 5mg
Brand: 源叶
SKU: T66221-5mg

Yuanye Research chemical CAS 161180-11-6 95% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T66221-5mg

Product model：5mg

level： 95% 5mg

Lead Time：30days

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Research chemical CAS 161180-11-6 95% 5mg

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