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Product introduction

HKI-357 是 EGFR 和 ERBB2 的不可逆双重抑制剂，IC50 分别为 34 nM 和 33 nM。HKI-357 抑制 EGFR 自磷酸化 (检测位点为 Y1068)，及 AKT 和 MAPK 磷酸化。

Specs ⸢ View details ⸥

Chinese name

HKI 357,ErbB2和EGFR的双重不可逆抑制剂

English name

HKI 357

Chinese alias

(2E)-N-[[4-[[(3-氯-4-[[3-氟苯基)甲氧基]苯基]氨基] -3-氰基-7-乙氧基-6-喹啉基] -4-(二甲基氨基) -2-丁烯酰胺

English alias

4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3-fluoro-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | A900842 | Q27256922 | YIB13317 | 2-Butenamide, N-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-3-cyano-7-ethoxy-6-quinolinyl

CAS number

848133-17-5

molecular formula

C31H29ClFN5O3

molecular weight

574.05 g/mol

Exact mass

≥98%(HPLC)

PSA

99.500 Å²

Logp

6.000

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MedMol HKI 357 98% 10mg

Name: MedMol HKI 357 98% 10mg
Brand: MedMol
SKU: T68959-10mg

MedMol HKI 357 98% 10mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T68959-10mg

Product model：10mg

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Lead Time：30days

sold 440 Items

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MedMol HKI 357 98% 10mg

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