凝血酶

T754968-20units

20units

from human plasma

凝血酶可用于重组RELM（抵抗素样分子家族成员）蛋白的表达和纯化。它被用作血小板在纤维蛋白原 和免疫染色分散。凝血酶用于凝血研究，医学研究，蛋白质结构分析和生化研究。它被用作血小板刺激物。应用： 凝血酶是一种Na+变构丝氨酸蛋白酶。它属于糜蛋白酶家族。凝血酶是由两条多肽链组成，一条含有36个氨基酸残基（A链），另一条有259个残基（B链），两条链通过二硫键共价连接。凝血酶是凝血因子IIa。它是一种丝氨酸内肽酶，水解肽链和酯键，尤其是在Arg羧基侧的。该酶将纤维蛋白原转化为纤维蛋白。产品含有EDTA和额外的稳定剂。 Thrombin is a Na + activated allosteric serine protease. It belongs to chymotrypsin family. Thrombin is made of two polypeptide chains of 36 (A chain) and 259 (B chain) residues that are covalently attached with a disulfide bond. Thrombin is a coagulation factor IIa. It is a serine endopeptidase that hydrolyzes peptide and ester bonds specifically at the carboxylic side of Arg. The enzyme converts fibrinogen to fibrin. The product contains EDTA and additional stabilizing agents. Application: Thrombin has been used in the expression and purification of recombinant RELM (resistin-like moleculefamily members. It has also been used in platelet spreading on fibrinogen and immunostaining. Thrombin is used in coagulation research, medical research, protein-structure analysis, and biochemical research. It has been used for the stimulation of the platelets.

凝血酶在凝血中有很重要的作用。它作为促凝血因子，能够将纤维蛋白原转化成不能溶解的纤维蛋白结块。通过激活蛋白质C，凝血酶可用作抗凝血剂。