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Product introduction

Tesirine intermediate-2 是 Tesirine (HY-128952) 的中间体。Tesirine (SG3249) 是一种吡咯苯并二氮卓 (PBD) 二聚体，是 DNA 小沟交联剂，具有很强的细胞毒性。Tesirine 可用于合成抗体偶联活性分子 (Antibody-Drug Conjugates (ADCs))，有效载荷的弹头成分是 SG3199 ，具有强抗癌细胞活性。 Tesirine mediate-2 is an intermediate of Tesirine (HY-128952). Tesirine (SG3249) is a pyrrole benzodiazepine (PBD) dimer, which is a DNA small groove crosslinking agent with strong cytotoxicity. Tesirine can be used to synthesize antibody drug conjugates (ADCs), and the payload's warhead component is SG3199, which has strong anti-cancer cell activity. Powder -20°C 3 years；In solvent -80°C 6 months，-20°C 1 month

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Chinese name

Tesirine intermediate-2

English name

Tesirine intermediate-2

Chinese alias

English alias

CAS number

1430738-34-3

molecular formula

C40H55N5O10Si

molecular weight

793.98 g/mol

Exact mass

≥99%

PSA

Logp

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