- exposure pathway： 口服(A302)。
- Toxicity summary： 萘呋胺阻断2型血清素（5-HT2）受体，从而抑制血清素诱导的血管收缩或血小板聚集。它也是一种代谢刺激剂，通过改善有氧葡萄糖代谢来保存缺血条件下的细胞功能。过量使用可能导致房室传导时间紊乱、室性心律失常、惊厥、急性肾功能衰竭或急性肝坏死(A302)。
- Regulatory information： REACH注册物质：状态：活跃 更新：16-02-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/22458
- Toxicity Data： LD50：1890 mg/kg（口服，大鼠）(L1001)
- Health Effects： 萘呋胺增加外周血液循环，例如在周围血管疾病（PAOD）、雷诺氏现象、脑血管疾病、老年人伴随意识混乱或行为障碍的弥漫性循环不全中。过量使用可能导致房室传导时间紊乱、室性心律失常、惊厥、急性肾功能衰竭或急性肝坏死（A302）。
- Symptoms and Signs： 惊厥、恶心和上腹痛、皮疹、肝炎或肝功能衰竭、草酸钙结石（A302，L1000）。
- Other safety information： 化学品评估：IMAP评估 - 2-呋喃丙酸，四氢-.alpha.-(1-萘基甲基)-，2-(二乙基氨基)乙酯：人体健康I级评估
- Hazard categories and classifications： 急性毒性 4 (100%)
- Carcinogen Classification： 对人类无致癌性迹象（未被IARC列出）。
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
Warm reminder：
Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！
Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.
Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！
Nafronyl 5mg
Yuanye Nafronyl 5mg, CAS 31329-57-4, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
