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Product introduction
NGB 2904 是一种有效,选择性, 可透过血脑屏障的多巴胺 D3 受体的拮抗剂,Ki 值为 1.4 nM。NGB 2904 对 D3 的选择性高于 D2,5-HT2,α1,D4,D1 和 D5 受体 (Ki=217,223,642,>5000,>10000 和 >10000 nM)。NGB 2904 可拮抗 Quinpirole 刺激的有丝分裂。 NGB 2904 is a potent, selective, orally active and brain-penetrated antagonist of dopamine D3 receptor, with a Ki of 1.4 nM. NGB 2904 shows selectivity for D3 over D2, 5-HT2, α1, D4, D1 and D5 receptors (Kis=217, 223, 642, >5000, >10000 and >10000 nM, respectively). NGB 2904 antagonizes Quinpirole-stimulated mitogenesis.
Chinese name
NGB 2904, D 3 受体拮抗剂
English name
NGB 2904
Chinese alias
-
English alias
CHEBI:92089 | F81743 | BRD-K05181084-003-02-9 | N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide | N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9hfluorene-2-carboxamide
CAS number
189060-98-8
molecular formula
C28H29Cl2N3O
molecular weight
494.46 g/mol
Exact mass
-
PSA
35.600 Ų
Logp
6.4
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MedMol NGB 2904 98% 10mg

MedMol NGB 2904 98% 10mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T78472-10mg
Product model:10mg
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Lead Time:30days
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