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利福霉素 B 是利福霉素类抗生素的一种，是细菌 RNA 合成的强效抑制剂，专门针对细菌 DNA 依赖性 RNA 聚合酶 (RNAP)。其作用机制是与 RNAP 的 β 亚基结合，从而阻碍 RNA 合成的延伸阶段，阻止重要细菌基因的转录。利福霉素 B 已被广泛用于微生物研究，以研究细菌转录调控、RNA 聚合酶动力学和抗生素耐药性机制。研究人员利用它的抑制活性来研究细菌 RNA 聚合酶的结构和功能，并开发出针对 RNA 合成的新型抗生素。此外，利福霉素 B 还是基因表达分析和 RNA 测序等分子生物学应用中的重要工具，利用其选择性抑制细菌 RNA 合成的能力来研究细菌基因调控和对环境线索的转录反应。此外，人们还探索了利福霉素 B 及其衍生物在生物技术中的潜在应用，包括重组蛋白质的生产和新型抗菌剂的开发。目前的研究工作仍在继续，以揭示利福霉素 B 作用机制的复杂细节，并探索其在微生物学和生物技术领域的多种应用 Application Rifamycin B (Rifaximin EP Impurity B) is a Rifamycin derivative as antibacterial agent.

Specs ⸢ View details ⸥

Chinese name

利福霉素B

English name

Rifamycin B

Chinese alias

English alias

CAS number

13929-35-6

molecular formula

C39H49NO14

molecular weight

755.8 g/mol

Exact mass

≥95%

PSA

228.000 Å²

Logp

4.800

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Research chemical CAS 13929-35-6 ≥95% 5mg

Name: Research chemical CAS 13929-35-6 ≥95% 5mg
Brand: 源叶
SKU: T83558-5mg

Research chemical CAS 13929-35-6 ≥95% 5mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T83558-5mg

Product model：5mg

level： ≥95% 5mg

Lead Time：30days

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Research chemical CAS 13929-35-6 ≥95% 5mg

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