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Product introduction

Y134 是一种选择性和具有口服活性的雌激素受体 (ER) 调节剂 (SERM)，对 ERα 和 ERβ 表现出强效拮抗剂活性。Y134 对 ERα (Ki=0.09 nM) 的选择性比对 ERβ (Ki=11.31 nM) 高 121.1 倍。Y134 抑制雌激素刺激的 ER 阳性人乳腺癌细胞的增殖。 Y134 is an estrogen receptor inhibitor that is selective and orally active, exhibiting strong antagonist activity against ERα and Erβ with Ki of 0.09 nM and 11.31 nM, respectively. The selectivity of Y134 for ERα is 121.1 times higher than that for ERβ. Y134 inhibited the proliferation of ER positive human breast cancer cells stimulated by estrogen.

Specs ⸢ View details ⸥

Chinese name

Y 134,雌激素受体调节剂（SERM）

English name

Y 134

Chinese alias

[6-羟基-2-(4-羟基苯基)苯并[b]噻吩-3-基]-[4-[4-(1-甲基乙基)-1-哌嗪基]苯基]甲酮

English alias

GTPL5430 | (6-hydroxy-2-(4-hydroxy-phenyl)benzo(b)thiophen-3-yl)-(4-(4-isopropylpiperazin-1-yl)-phenyl)methanone | BRD-K94832621-001-01-5 | HMS3413P21 | [6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methano

CAS number

849662-80-2

molecular formula

C28H28N2O3S

molecular weight

472.6 g/mol

Exact mass

PSA

92.300 Å²

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MedMol Y134 98% 10mg

Name: MedMol Y134 98% 10mg
Brand: MedMol
SKU: T87837-10mg

MedMol Y134 98% 10mg, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T87837-10mg

Product model：10mg

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Lead Time：30days

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MedMol Y134 98% 10mg

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