- exposure pathway： 口服
- Toxicity summary： 与摄入的马兜铃酸（AA）代谢物与DNA结合相关的致癌和致突变效应已在体外和体内广泛描述，导致AA被分类为遗传毒性致癌物。在伴有BEN（巴尔干地方性肾病）患者的肾皮质和尿路上皮肿瘤组织中发现的AA衍生的DNA加合物，与p53肿瘤抑制基因突变谱中A:T到T:A转换的主导地位相关。（A15444）AA是一种肾毒性和致癌性化合物，已被证明在体外和体内都具有遗传毒性和致突变性。肾毒性化合物马兜铃酸在啮齿动物和人类之间的毒性和致癌性表明其作用机制具有物种依赖性。AA对细胞周期有相似的影响...
- Regulatory information： 加州化妆品安全计划(CSCP)报告成分：报告 - 无论成分在产品中的预期功能如何
- Hazard categories and classifications： 急性毒性3（100%）
- Carcinogen Classification： 马兜铃酸，定义为马兜铃属物种的提取物，包含马兜铃酸I和马兜铃酸II的混合物，被IARC分类为对人类致癌（1组）。（L135）
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Research chemical CAS 313-67-7 1ml
Yuanye Research chemical CAS 313-67-7 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
