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Product introduction
根据州或联邦政府标签要求,乙酰氧肟酸可导致发育毒性。
Chinese name
乙酰氧肟酸, 细菌脲酶抑制剂
English name
N-hydroxyacetamide
Chinese alias
醋羟胺酸, N-羟基乙酰胺,乙酰异羟肟酸
English alias
EINECS 208-913-8 | Lithostat (TN) | Spectrum_000020 | AB01014 | ACETOHYDROXAMIC ACID [HSDB] | ACETOHYDROXAMIC ACID [USP-RS] | SPBio_000098 | Acethydroxamsaure | acetohydroxamic acid | Acetohydroxamic acid (USAN:USP:INN) | Acetohydroxamic acid (USP/INN) |
CAS number
546-88-3
molecular formula
C2H5NO2
molecular weight
75.07
Exact mass
10mM in DMSO
PSA
49.3
Logp
-1.6
Safety
  • Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
  • Regulatory information: 加州化妆品安全计划(CSCP)报告成分:报告 - 无论成分在产品中的预期功能如何
  • interaction: 体外研究表明,乙酰氧肟酸和乌洛托品在抑制尿素酶产生变形杆菌属引起的pH值升高方面具有协同作用,并且乙酰氧肟酸增强了乌洛托品对这些细菌的抗菌效果...
  • Human toxicity extract: 尚未报告醋羟肟酸过量。然而,如果发生过量,应预期血小板和/或白细胞同时减少;网状红细胞计数可能升高,并且可能发生严重溶血。
  • non-human toxicity value: LD50 大鼠口服 4.8 g/kg
  • Hazard categories and classifications: Repr. 1B (96.1%)
  • Non-human toxic extract: 当药物以500毫克/公斤的剂量对小鼠皮下给药60-100天时,未出现毒性证据;然而,当药物以1克/公斤的剂量皮下给药时,出现了累积毒性证据,死亡平均发生在21天。
  • Antidote and first aid: 过量治疗:应停止给药。目前已知乙酰氧肟酸没有特定的解毒剂。推荐的治疗包括以下内容:监测-密切监测血液状况;特定治疗-必要时进行对症治疗。如需要可进行输血。透析(考虑可能但尚未证实)。
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2016.02.015
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Research chemical CAS 546-88-3 1ml

Yuanye Research chemical CAS 546-88-3 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T90184-1ml
Product model:1ml
level: 1ml
Lead Time:30days
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