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Product introduction
4-苯丁酸是一种一元羧酸,其结构为在C-4位被苯基取代的丁酸。它是一种组蛋白去乙酰化酶抑制剂,具有抗癌活性。它抑制胶质瘤细胞的增殖、侵袭和迁移并诱导细胞凋亡。它还抑制蛋白质异戊二烯化,消耗血浆谷氨酰胺,通过γ-珠蛋白基因的转录激活增加胎儿血红蛋白的产生,并影响hPPARγ激活。它具有抗肿瘤药物、前药、EC 3.5.1.98 (组蛋白去乙酰化酶)抑制剂和细胞凋亡诱导剂的作用。它与丁酸功能相关。它是4-苯丁酸的共轭酸。
Chinese name
4-苯基丁酸
English name
4-phenylbutanoic acid
Chinese alias
-
English alias
4-Phenyl-n-butyrate | CCG-39733 | FT-0673736 | NCGC00018113-04 | NSC295 | NSC-295 | s3592 | gamma-Phenylbutanoic acid | SpecPlus_000814 | CHEBI:41500 | OBKXEAXTFZPCHS-UHFFFAOYSA- | 2-methyl-1-phenyl-propan-2-amine | g-Phenylbutyrate | g-phenyl-Butyrate |
CAS number
1821-12-1
molecular formula
C10H12O2
molecular weight
164.20
Exact mass
-
PSA
37.3
Logp
2.4
Safety
  • Hazard summary: 皮肤和强眼刺激物;[Alfa Aesar MSDS] 参见丁酸。
  • Regulatory information: 新西兰化学品清单状态:苯丁酸:没有单独批准,但可在适当的团体标准下使用
  • Hepatotoxicity: 可能性评分:E(不太可能引起临床上明显的肝损伤,但使用经验有限)。
  • Hazard categories and classifications: STOT SE 3 (75%)
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Research chemical CAS 1821-12-1 1ml

Yuanye Research chemical CAS 1821-12-1 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T90593-1ml
Product model:1ml
level: 1ml
Lead Time:30days
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