- Toxicity summary： 丙二酸是脂肪和蛋白质代谢中的关键中间体，丙二酸的异常会导致丙二酸尿症。这种代谢性疾病归因于酶促反应中从甲酰 -3-甲基丁酰辅酶 A 到琥珀酰辅酶 A 的转化受阻。体内丙二酸的积累已被证明具有毒性。
- Health Effects： 长期高水平的丙二酸与至少 5 种先天性代谢错误有关：包括乙酰辅酶 A 脱羧酶缺乏症、丙二酸尿症、甲酰 -3-甲基丁醛脱水酶缺乏症、甲酰 -3-甲基丁酸尿症和由于钴胺素相关疾病引起的甲酰 -3-甲基丁酸尿症。
- Hazard categories and classifications： STOT SE 3 (100%)
- Carcinogen Classification： 对人类无致癌性指示（未列入 IARC）。
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Research chemical CAS 516-05-2 1ml
Yuanye Research chemical CAS 516-05-2 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
