- Harmful effect： 最近一项研究强调，同时使用替扎尼定和扎鲁司特可能导致低血压，可能增加跌倒和骨折的风险。
- Toxicity summary： 临床研究已记录，80mg高剂量扎鲁司特可转氨酶水平升高。动物研究表明，犬扎鲁司特剂量500mg/kg和小鼠2000mg/kg未导致任何报告死亡。根据制造商指南，4例报告的扎鲁司特药物过量的患者服用200mg后存活。这些病例出现轻度症状，包括皮疹和胃部不适。在急性扎鲁司特过量的情况下，建议对患者进行干预包括洗胃、密切临床监测和支持治疗。
- Hepatotoxicity： 可能性评分：C（可能是临床明显肝损伤的原因）。
- Primary Hazards： 未分类
- Hazard categories and classifications： 水生慢性4 (92.9%)
- Drug Induced Liver Injury： 参考文献：DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation： ◉ 对哺乳和母乳的影响
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Research chemical CAS 107753-78-6 1ml
Yuanye Research chemical CAS 107753-78-6 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
