Share to

Overview

Specs

Technical Documents

Articles

reviews

Consult

returns

Product introduction

产品介绍： TL13-12 是一种强效的 ALK-PROTAC 降解物，抑制 ALK 活性，其 IC50 值为 0.69 nM，并促进其他激酶的降解，包括 Aurora A、FER、PTK2 和 RPS6KA1，其 IC50 值分别为 13.5 nM、5.74 nM、18.4 nM 和 65 nM。TL13-12 由 TAE684 (HY-10192) 和 Cereblon 配体 Pomalidomide (HY-10984) 结合而成。

Specs ⸢ View details ⸥

Chinese name

TL 13-12

English name

TL 13-12

Chinese alias

N-(2-(2-(2-(4-(4-((5-5-氯-4-((2-(异丙基磺酰基)苯基)氨基)嘧啶-2-基)氨基)-3-甲氧基苯基)哌嗪-1-基)乙氧基)乙氧基)乙基)-2-((2-(2,6-二氧代哌啶-3-基)-1,3-二氧异吲哚基-4-基)氨基)乙酰胺

English alias

N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-3-methoxyphenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamide

CAS number

2229037-04-9

molecular formula

C45H53ClN10O10S

molecular weight

961.48 g/mol

Exact mass

≥98%(HPLC)

PSA

251.000 Å²

Logp

4.600

Technical Documents

「No technical documents」

「No upstream and downstream information yet」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！

2-chloro-3, 4-dimethoxybenzoic acid ≥98%(HPLC) 5mg

Name: 2-chloro-3, 4-dimethoxybenzoic acid ≥98%(HPLC) 5mg
Brand: 麦克林
SKU: T936428-5mg

2-chloro-3, 4-dimethoxybenzoic acid ≥98%(HPLC) 5mg CAS 2229037-04-9, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：T936428-5mg

Product model：5mg

level：

Lead Time：30days

sold 975 Items

Ask Solution engineer

Qty

2-chloro-3, 4-dimethoxybenzoic acid ≥98%(HPLC) 5mg

Recommended for you