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Product introduction
尼鲁米德是一种C-硝基化合物、咪唑烷酮和三氟甲基苯的成员。它具有雄激素拮抗剂和抗肿瘤药物的作用。
Chinese name
Nilutamide, 雄激素受体拮抗剂
English name
5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
Chinese alias
尼鲁米特 | 5,5-二甲基-3-[4-硝基-3-(三氟甲基)苯基]-2,4-咪唑烷二酮 | 尼鲁米特
English alias
5,5-Dimethyl-3-(4-nitro-3-(trifluoromethyl)-phenyl)imidazolidine-2,4-dione | 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione | BDBM50135912 | KBio2_007241 | KBioGR_001100 | Prestwick0_000928 | RU 23908-10 | SR-01000076034 | N 853
CAS number
63612-50-0
molecular formula
C12H10F3N3O4
molecular weight
317.22
Exact mass
-
PSA
95.2
Logp
2
Safety
  • exposure pathway: 迅速且完全吸收,产生高而持久的血浆浓度。
  • Toxicity summary: 尼鲁米德与雄激素竞争雄激素受体结合,从而阻断肾上腺和睾丸来源的雄激素对正常和恶性前列腺组织生长的刺激作用。这种雄激素受体阻断可能通过抑制雄激素依赖的DNA和蛋白质合成,导致生长停滞或暂时性肿瘤消退。
  • Hepatotoxicity: 可能性评分:C(可能是明显肝损伤的原因)。
  • Symptoms and Signs: 过量症状包括头晕、全身不适、头痛、恶心和呕吐。
  • Hazard categories and classifications: Repr. 1B (97.6%)
  • Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2016.02.015
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Research chemical CAS 63612-50-0 1ml

Yuanye Research chemical CAS 63612-50-0 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T94240-1ml
Product model:1ml
level: 1ml
Lead Time:30days
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