
- exposure pathway: 迅速且完全吸收,产生高而持久的血浆浓度。
- Toxicity summary: 尼鲁米德与雄激素竞争雄激素受体结合,从而阻断肾上腺和睾丸来源的雄激素对正常和恶性前列腺组织生长的刺激作用。这种雄激素受体阻断可能通过抑制雄激素依赖的DNA和蛋白质合成,导致生长停滞或暂时性肿瘤消退。
- Hepatotoxicity: 可能性评分:C(可能是明显肝损伤的原因)。
- Symptoms and Signs: 过量症状包括头晕、全身不适、头痛、恶心和呕吐。
- Hazard categories and classifications: Repr. 1B (97.6%)
- Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
- Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2016.02.015
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Research chemical CAS 63612-50-0 1ml
Yuanye Research chemical CAS 63612-50-0 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.




