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Product introduction
BI-9627 is potent sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor, with IC 50 s of 6 and 31 nM in intracellular pH recovery (pHi) and human platelet swelling assays, respectively. BI-9627 displays >30-fold selectivity against NHE2 and with no measurable inhibitory activity against the NHE3 isoform. BI-9627 shows low DDI (agent-agent interaction) potential, excellent pharmacokinetics in rat and dog, and remarkably potent activity in the isolated heart model of ischemia-reperfusion injury Form:Solid IC50& Target:IC50: 6 nM (NHE1 in intracellular pH recovery assay), 31 nM (NHE1 in human platelet swelling assay)
Chinese name
BI-9627
English name
BI-9627
Chinese alias
-
English alias
-
CAS number
1204329-34-9
molecular formula
C16H19F3N4O2
molecular weight
356.34 g/mol
Exact mass
≥98%
PSA
102.000 Ų
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Research chemical CAS 1204329-34-9 1ml

Yuanye Research chemical CAS 1204329-34-9 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T95292-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 560 Items
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