Broflanilide is a potential insecticide and metabolized to Desmethyl-Broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA Receptor , and inhibits S. litura RDL GABAR, with an IC 50 value of 1.3 nM. In Vitro Broflanilide is an insecticide and metabolized to desmethyl-broflanilide, which is a potent and selective antagonist at the insect resistant-to-dieldrin (RDL) GABA receptor, and inhibits S. litura RDL GABAR, with an IC 50 value of 1.3 nM. Desmethyl-broflanilide shows weak activity against human GABA A α1β2γ2 receptor, the mammalian GABA A α1β3γ2 receptor and human glycine receptor (GlyR) α1β with IC 50 s of >3 μM, and less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G (IC 50 s, 0.706, 0.149 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid