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Product introduction
GSK481是RIP1(Receptor Interacting Protein Kinase1, RIPK1)抑制剂,抑制RIP1以阻碍细胞坏死。 Information GSK481 GSK481 is a RIP1(Receptor Interacting Protein Kinase1, RIPK1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death. Targets RIP1 In vitro GSK481 can inhibit RIP1 WT S166 phosphorylation in human vs mouse plasmids overexpressed in HEK293T cells. GSK481 has approximately equivalent RIP1 FP potencies against human and cynomolgus monkey RIP1 but was >100-fold less potent against nonprimate RIP.
Chinese name
GSK481
English name
GSK481
Chinese alias
-
English alias
3-​Isoxazolecarboxamide​,5-​(phenylmethyl)​-​N-​[(3S)​-​2,​3,​4,​5-​tetrahydro-​5-​methyl-​4-​oxo-​1,​5-​benzoxazepin-​3-​yl]​-
CAS number
1622849-58-4
molecular formula
C21H19N3O4
molecular weight
377.39 g/mol
Exact mass
10mM in DMSO
PSA
84.700 Ų
Logp
2.545
Technical Documents
「No technical documents」
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Research chemical CAS 1622849-58-4 1ml

Yuanye Research chemical CAS 1622849-58-4 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T96247-1ml
Product model:1ml
level: 1ml
Lead Time:30days
sold 178 Items
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