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Product introduction
GNE-6468 is a highly potent and selective RORγ (RORc) inverse agonist with an EC 50 value of 13 nM for HEK-293 cell. GNE-6468 exhibits an EC 50 of 30 nM for IL-17 PBMC In Vivo GNE-6468 (compound 28) displays high predicted clearance values in human and rodent hepatocytes (CL hep = 17 and 42 mL/min/kg, respectively) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:ROR-γ 2 nM (EC 50 )
Chinese name
GNE-6468
English name
GNE-6468
Chinese alias
-
English alias
-
CAS number
1677668-27-7
molecular formula
C23H16ClN3O4
molecular weight
433.84 g/mol
Exact mass
≥98%
PSA
105.000 Ų
Logp
5.700
Technical Documents
「No technical documents」
Related
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Research chemical CAS 1677668-27-7 1ml

Yuanye Research chemical CAS 1677668-27-7 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T96379-1ml
Product model:1ml
level: 1ml
Lead Time:30days
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