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Product introduction
2-NBDG是一个荧光标记的2-脱氧葡萄糖的类似物,它可以作为评估细胞糖原代谢的示踪物。 糖原是组织中以保持细胞活性和稳态所必需的能源来源。糖原代谢是很多疾病的重要指标,它可以随着病理情况而改变,因此评估糖原代谢可以作为疾病进程中的重要指征。 在体外,2-NBDG可以被用于多种细胞,比如HepG2人源肝癌细胞,L6大鼠骨骼肌细胞,MCF-7乳腺癌上皮细胞和星形胶质细胞等。它也可以用于多种疾病模型,比如癫痫大鼠,高血糖症,糖尿病和癌细胞异种移植小鼠模型。 2-NBDG可以通过糖原转运蛋白进入细胞,随后被己糖激酶磷酸化,滞留在细胞中。活细胞摄入2-NBDG可以通过流式细胞计数检测细胞发出的荧光,而细胞内的2-NBDG的浓度使用荧光微孔板分析。它也可以简单地通过荧光显微镜或者CCD相机检测。 fluorescent indicator for monotoring of glucose uptake into living cells
Chinese name
2-(N-7-硝基-2,1,3-苯并噁二唑-4-氨基)-2-脱氧-D-葡萄糖(2-NBDG)
English name
2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-2-deoxy-D-glucose(2-NBDG)
Chinese alias
2-[N-(7-硝基苯-2-氧杂-1,3-二唑-4-基)氨基]-2-脱氧D-葡萄糖 | 2-脱氧-2-[(7-硝基-2,1,3-苯并恶二唑-4-基)氨基]-D-葡萄糖
English alias
2-NBDG | UNII-JE4F4P486R | MolMap_000037 | PD102201 | HY-116215 | JE4F4P486R | 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxy-D-glucose | (2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-2-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanal
CAS number
186689-07-6
molecular formula
C12H14N4O8
molecular weight
342.26 g/mol
Exact mass
≥97%
PSA
195.000 Ų
Logp
-1.400
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Research chemical CAS 186689-07-6 1ml

Yuanye Research chemical CAS 186689-07-6 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T96606-1ml
Product model:1ml
level: 1ml
Lead Time:30days
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