NU6300 is a covalent, irreversible and ATP-competitive CDK2 inhibitor with an IC 50 value of 0.16 μM. NU6300 can be used for the research of eukaryotic cell cycle- and transcription-related In Vitro NU6300 (50 μM; 0-1 hour) covalently modifies and irreversible inhibits CDK2. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: SKUT-1B cells Concentration: 50 μM Incubation Time: 0-1 hour Result: Affected retinoblastoma tumor suppressor protein (Rb) phosphorylation in SKUT-1B cells and covalently binded with CDK2. Form:Solid IC50& Target:CDK2