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Product introduction
TSU-68 (SU6668; Orantinib)是多酪氨酸激酶受体抑制剂,对PDGFR自磷酸化抑制性最强,Ki为8 nM,还能相对弱地抑制VEGF-R1和FGF-R1。An antiproliferating agent and ATP-competitive PDGFR, Flk-1/KDR (VEGF), and FGFR inhibitor TSU-68 (SU6668, Orantinib) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3. An antiproliferating agent and ATP-competitive PDGFR, Flk-1/KDR (VEGF), and FGFR inhibitor
Chinese name
TSU-68(SU6668,Orantinib),PDGFR抑制剂, 表皮生长因子受体抑制剂
English name
TSU-68 (SU6668, Orantinib)
Chinese alias
-
English alias
3-{2,4-Dimethyl-5-[(Z)-(2-Oxo-1,2-Dihydro-3h-Indol-3-Ylidene)methyl]-1h-Pyrrol-3-Yl}propanoic Acid | J-502593 | ORANTINIB [WHO-DD] | H.P. 209 | NCGC00387029-01 | 9RL37ZZ665 | J-013813 | CHEBI:94436 | 3-(2,4-DIMETHYL-5-(((3Z)-2-OXO-1,2-DIHYDRO-3H-INDOL-3-Y
CAS number
252916-29-3
molecular formula
C18H18N2O3
molecular weight
310.35 g/mol
Exact mass
-
PSA
82.200 Ų
Logp
2.200
Technical Documents
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Research chemical CAS 252916-29-3 1ml

Yuanye Research chemical CAS 252916-29-3 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:T97527-1ml
Product model:1ml
level: 1ml
Lead Time:30days
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