SARS-CoV-IN-2 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-2 shows anti-Coronavirus activity with an EC 50 of 1.9 μM in Vero cells. SARS-CoV-IN-2 inhibits the 3D7 and W2 strains of P. falciparum with IC 50 s of 21.5 and 30 nM; and IC 90 s of 51.0 and 99.9 nM; respectively. SARS-CoV-IN-2 reduces HIV-1 -induced cytopathic effect with an EC 50 of 2.9 μM in MT-4 cells. Antimalarial and Antiviral Activities In Vitro SARS-CoV-IN-2 (Compound 3) inhibits in vitro growth of Plasmodium falciparum far better than Chloroquine (CQ). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Plasmodium HIV-1