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Product introduction

UCSF924 is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC 50 of 4.2 nM. UCSF924 has a high-affinity with a K i value of 3 nM for DRD4 and shows no measurable affinity for D2, D3 or the F261V/L328F D4 mutant. UCSF924 is a 7.4-fold bias toward arrestin over Gαi/o signaling, referenced to quinpirole Form:Solid IC50& Target:Ki: 3 nM (dopamine D4 receptor)

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Chinese name

UCSF924

English name

UCSF924

Chinese alias

加州大学旧金山分校924

English alias

CAS number

1434515-70-4

molecular formula

C20H22N2O2

molecular weight

322.40 g/mol

Exact mass

≥99%

PSA

Logp

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