N-DBCO-N-bis(PEG2-C2-acid) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。N-DBCO-N-bis(PEG2-C2-acid) 是一种点击化学试剂。它含有 DBCO 基团，可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。 N-DBCO-N-bis(PEG2-acid) is a branched PEG derivative containing a DBCO and two PEG2-acid chains attached to a central nitrogen group. The DBCO group allows for the compound to participate in copper-free Click Chemistry reactions. The addition of the carboxylic acid groups allows for reactions with primary amine groups using activators such as EDC or DCC to form a stable amide bond.