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Product introduction

Sodium stibogluconate 是一种有效的蛋白酪氨酸磷酸酶 (Phosphatase) 抑制剂。它在10，100 和 100 μg/mL 时分别抑制 99% 的 SHP-1，SHP-2 和 PTP1B 活性。 Sodium stibogluconate (SSG, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001), a pentavalent antimony derivative, is a potent and selective inhibitor of protein tyrosine phosphatase (PTPase). Sodium stibogluconate inhibits 99% of Src homology 2 domain-containing phosphatase 1 (SHP-1) activity at 10 μg/ml and similar degrees of inhibition of SHP-2 and PTP1B requires 100 μg/ml. Sodium stibogluconate is a drug used in treatment of leishmaniasis.

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Chinese name

Stibogluconate sodium

English name

Stibogluconate sodium

Chinese alias

葡萄糖酸锑钠

English alias

CAS number

16037-91-5

molecular formula

C12H17O17Sb2·3Na·9H2O

molecular weight

907.88 g/mol

Exact mass

10mM in Water

PSA

Logp

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