杀黑星菌素A，一种抗生素和抗真菌化合物，被认为是| E的潜在抑制剂。大肠杆菌| H | + | -ATPase。实验表明，该化合物强烈抑制ATP驱动的质子转运和ATP水解。更详细的研究表明Venturicidin A作用于膜区F | 0 |。据报道，纯化的牛F | 0 |引起电压敏感的K | + |通道。杀黑星菌素A展示了显着降低通道开放概率的能力。杀黑星菌素A是ATP5的抑制剂。 Venturicidin A, an antibiotic and antifungal compound, has been noted to be a potential inhibitor of|E. coli|H|+|-ATPase. Experiments suggest that this compound strongly inhibits ATP-driven proton transport and ATP hydrolysis. More detailed studies show that Venturicidin A acts on the membrane sector F|0|. Purified bovine F|0|has been reported to cause voltage sensitive K|+|channels. Venturicidin A demonstrates the ability to drastically decrease the open probability of the channel. Venturicidin A is an inhibitor of ATP5.