伐地那非-d5是氘标记的磷酸二酯酶抑制剂，对PDE5和PDE1具有选择性（分别为IC | 50 | = 0.7和180 nM）。维地那非在结构和功能上与西地那非和他达拉非密切相关。抑制PDE酶可防止次级信使分子分解，延长信号转导及其后续作用。该化合物可用于动力学同位素效应研究，也可作为NMR实验中的内标。 Vardenafil-d5 is a deuterium-labeled phosphodiesterase inhibitor that is selective for PDE5 and PDE1 (IC|50|= 0.7 and 180 nM, respectively). Verdenafil is closely related to sildenafil and tadalafil in structure as well as function. Inhibition of PDE enzymes prevents the breakdown of secondary messenger molecules, prolonging signal transduction and its subsequent effects. This compound is useful in kinetic isotope effect studies and as an internal standard in NMR experiments.