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Product introduction
双异丙胺是一种一元羧酸酰胺,是在4位被二异丙氨基取代、在2位被苯基取代、在2位被吡啶-2-基取代的丁酰胺。它用作抗心律失常药物。它具有抗心律失常药物的作用。它是吡啶类、一元羧酸酰胺和三级胺化合物的成员。
Chinese name
双异丙吡胺
English name
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide
Chinese alias
-
English alias
2-Pyridineacetamide,a-[2-(diisopropylamino)ethyl]-a-phenyl- (7CI,8CI); (RS)-disopyramide; (?à)-Disopyramide; 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)butyramide; Dicorantil; Disopyramide; H 3292; Isorythm; Lispine; Ritmilen; Ritmodan; SC7031; Searle 703;
CAS number
3737-09-5
molecular formula
C21H29N3O
molecular weight
339.5
Exact mass
-
PSA
59.2
Logp
3.2
Safety
  • Harmful effect: 尽管罕见(<1%),但在病例报告中有人报告了不良反应,如粒细胞缺乏症、胆汁淤积性黄疸、恶性心律失常和其他心电图异常。
  • Toxicity summary: 尽管仅基于理论考虑,可静脉给予 NaHCO3 50 mmol,每 5 至 10 分钟重复一次。主要目标是维持动脉 pH 在 7.4 至 7.5。药物逆转机制可能是多因素的,如提高血液 pH、增加血浆钠浓度和降低血浆钾浓度。
  • Regulatory information: 新西兰 EPA 化学品状态清单:丙吡胺:没有单独批准,但可在适当的团体标准下使用
  • Hepatotoxicity: 可能性评分:B(罕见但可能是临床上明显的肝损伤的原因)。
  • Other safety information: 化学评估: IMAP评估 - 2-吡啶乙酰胺,.alpha.-[2-[双(1-甲基乙基)氨基]乙基]-.alpha.-苯基-: 人类健康I级评估
  • Hazard categories and classifications: Repr. 2 (90.5%)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到相关已发表信息。
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Research chemical CAS 3737-09-5 ≥98%; 1g

Research chemical CAS 3737-09-5 ≥98%; 1g; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥98%; 1g.

item number:V34315-1g
Product model:1g
level: ≥98%; 1g
Lead Time:30days
sold 30 Items
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