
- Storage conditions: 储存在40°C (104°F)以下,最好在15-30°C (59-86°F)之间,除非制造商另有说明。储存在密闭良好的容器中。
- Disposal method: SRP:在审查时,土地处理或填埋(卫生填埋)处置实践的标准正在重大修订中。在实施废物残渣(包括废物污泥)的土地处置之前,咨询环境监管机构以获取可接受的处置实践指导。
- Ambient water concentration: 虽然未找到关于甲苯妥英的特定数据(SRC, 2007),但文献表明,一些来自人和兽医治疗的药物活性化合物在市政污水处理厂中不能被完全去除,因此被排放到受纳水体中(1)。废水处理过程通常不是为了从废水中去除它们而设计的(2)。选定的有机废物化合物可能降解成新的更持久的化合物,这些化合物可能被释放出来,替代或附加于母体化合物(2)。
- FDA Requirements: 具有治疗等效性评估的批准药物产品清单确定了已停产的药物产品。美芬妥英被列入此清单。
- Hazard categories and classifications: 特定靶器官毒性-单次接触 3 (93.3%)
- Non-human toxic extract: /实验室动物:发育或生殖毒性/ ...在妊娠第10天,给怀孕的瑞士ICR小鼠腹膜内注射等摩尔剂量的d-或l-美芬妥英或尼凡诺尔。l-尼凡诺尔处理组观察到胎儿吸收增加8倍,胎儿体重显著下降11%,而其他处理组未观察到或仅观察到最小毒性。
- Antidote and first aid: /SRP:/ 高级治疗:对于意识不清、严重肺水肿或严重呼吸窘迫的患者,考虑经口或经鼻气管插管进行气道控制。使用气囊面罩装置进行正压通气技术可能有益。考虑对肺水肿进行药物治疗...。对于严重支气管痉挛,考虑给予β激动剂如沙丁胺醇...。监测心律并根据需要治疗心律失常...。开始静脉注射D5W /SRP: "保持通畅",最小流速/。如果出现低血容量迹象,使用0.9%生理盐水(NS)或乳酸盐林格氏液。对于伴有低血容量体征的低血压,谨慎给予液体。注意液体过载的迹象...。用地西泮或劳拉西泮治疗癫痫...。使用...
- Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2016.02.015
- Populations at Special Risk: 在苯妥英等剂量给药后,慢性尿毒症患者的总血浆苯妥英浓度低于非尿毒症患者,这表明尿毒症患者对该药物的代谢处置发生改变。/苯妥英/
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Research chemical CAS 50-12-4 ≥98%; 25mg
Research chemical CAS 50-12-4 ≥98%; 25mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥98%; 25mg.




