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Product introduction

VU0238441 是一种泛 muscarinic acetylcholine receptor (mAChR) 的正向变构调节剂 (PAM)，对于M5、M3、M2、M1和M4的EC50值分别为2.1 μM、2.2 μM、2.8 μM、3.2 μM 和 >10 μM。 Information VU0238441 is a panmuscarinic acetylcholine receptor (mAChR)positive allosteric modulator (PAM) with EC50 of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and >10 μM for M5, M3, M2, M1 and M4, respectively. Targets mAChR M5 (Cell-free assay); mAChR M3 (Cell-free assay); mAChR M2 (Cell-free assay); mAChR M1 (Cell-free assay); mAChR M4 (Cell-free assay) ;2.1 μM; 2.2 μM; 2.8 μM; 3.2 μM; >10 μM

Specs ⸢ View details ⸥

Chinese name

VU0238441

English name

VU0238441

Chinese alias

English alias

1H-Indole-2,3-dione,7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]-

CAS number

85511-68-8

molecular formula

C16H9ClF3NO2

molecular weight

339.7 g/mol

Exact mass

10mM in DMSO

PSA

37.400 Å²

Logp

4.066

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