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Product introduction
JNJ 28871063 hydrochloride 是一种具有口服活性、高选择性和 ATP 竞争性的 pan-ErbB 激酶抑制剂,对 ErbB1、ErbB2 和 ErbB4 的 IC50 值分别为 22 nM、38 nM 和 21 nM。 JNJ 28871063 hydrochloride 抑制 EGFR 和 ErbB2 中功能重要的酪氨酸残基的磷酸化。 JNJ 28871063 hydrochloride 可穿过血脑屏障,在过度表达 EGFR 和 ErbB2 的人类肿瘤异种移植模型中具有抗肿瘤活性。
Chinese name
JNJ 28871063 hydrochloride
English name
JNJ 28871063 hydrochloride
Chinese alias
5E-4-氨基-6-(4-苄氧基-3-氯苯基氨基)嘧啶-5-羧醛N-(2-吗啉-4-基乙基)肟盐酸盐 | JNJ 28871063 盐酸盐
English alias
5E-4-Amino-6-(4-benzyloxy-3-chlorophenylamino)pyrimidine-5-carboxaldehydeN-(2-morpholin-4-ylethyl) oxime hydrochloride
CAS number
944342-90-9
molecular formula
C24H27ClN6O3•HCl
molecular weight
519.42 g/mol
Exact mass
≥97%(HPLC)
PSA
-
Logp
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Consultation

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Service Hotline:400-6226-992 ,We will handle it for you as soon as possible, thank you for your support and trust.!

Research chemical ≥97%; HPLC; 50mg

Research chemical ≥97%; HPLC; 50mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: ≥97%; HPLC; 50mg.

item number:V65813-50mg
Product model:50mg
level: ≥97%; HPLC; 50mg
Lead Time:30days
sold 698 Items
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