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物理描述 | 1,2-二氨基环己烷呈现为清澈至浅黄色液体。对眼睛、皮肤、口腔、喉咙和胃有腐蚀性。蒸气可能刺激眼睛。
Chinese name
1,2-环己二胺
English name
cyclohexane-1,2-diamine
Chinese alias
1,2-二氨基环己烷 (顺反混合物)
English alias
FT-0647969 | VS-08529 | (1R,2R)-cyclohexane-1,2-diamine;(1r,2r)-(-)-1,2-cyclohexanediamine | (rel)-Oxaliplatin | DACH | DTXCID707301 | FT-0604562 | Pyridoxal phosphate (calcium salt) | 6-Methoxypyridine-2-carboxylicacidhydrazide | Cyclohexanediamine1,2-cy
CAS number
694-83-7
molecular formula
C6H14N2
molecular weight
114.19
Exact mass
≥99%
PSA
52
Logp
-0.3
Safety
  • DOT label: 腐蚀性
  • Health hazard: 有毒和/或腐蚀性;吸入、摄入或皮肤接触该物质可能导致严重伤害或死亡。溴乙酸甲酯(UN2643)是一种眼睛刺激物/催泪剂(引起流泪)。接触熔融物质可能导致皮肤和眼睛严重烧伤。避免任何皮肤接触。火灾可能产生刺激性、腐蚀性和/或有毒气体。灭火或稀释水 runoff 可能具有腐蚀性和/或毒性,并造成环境污染。(ERG, 2024)
  • Hazard summary: 腐蚀性物质;[CAMEO] 从一项4小时致死浓度研究中大鼠恢复期的效果包括皮肤损伤、鼻分泌物和呼吸困难;在为期2周的吸入研究中观察到鼻粘膜病变;未观察到其他大体或组织病理学变化;基于对兔子的研究,被认为是重度皮肤和中度眼睛刺激物;对豚鼠皮肤无致敏作用;皮肤LD50(测试物质69.5% 1,6-己二胺和30.5% 1,2-二氨基环己烷)=7500 mg/kg,在白兔中引起严重刺激和坏死;[EPA HPVIS] 在28天大鼠喂养试验中,最高测试剂量(500 mg/kg)的观察结果包括肝脏颜色变浅和肝酶升高;窝仔数减少和产后...
  • reactive group: 胺类、膦类和吡啶类
  • First aid measures: 参考"一般急救"部分。特定急救:对于腐蚀性物质,如接触,立即用流动水冲洗皮肤或眼睛至少30分钟。可能需要额外冲洗。从皮肤上清除凝固的熔融材料需要医疗协助。(ERG, 2024)
  • Harmful effect: 毒性肺炎 - 因吸入金属烟雾或有毒气体和蒸汽引起的肺部炎症。
  • Regulatory information: 新西兰EPA化学品状态清单:1,2-环己二胺:没有单独批准,但可在适当的团体标准下使用
  • fire hazard: 可燃材料:可燃烧但不易点燃。加热时,蒸气可能与空气形成爆炸性混合物:室内、室外和下水道有爆炸危险。标有(P)的物质在加热或涉及火灾时可能发生爆炸性聚合。腐蚀性物质接触金属可能释放易燃氢气。容器受热可能爆炸。溢流可能污染水道。物质可能以熔融形式运输。(ERG, 2024)
  • fire fighting: FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)
  • Toxicity Data: 大鼠半数致死浓度(LCLo) = 3,200 mg/m3/4h
  • reactivity profile: 1,2-二氨基环己烷是一种胺。胺是化学碱。它们中和酸形成盐和水。这些酸碱反应是放热的。每摩尔胺在中和过程中释放的热量很大程度上与胺作为碱的强度无关。胺可能与异氰酸酯、卤代有机物、过氧化物、酚类(酸性)、环氧化物、酸酐和酰卤不相容。胺与强还原剂(如氢化物)结合会产生易燃的氢气。
  • Isolation and evacuation: 火灾:如果涉及罐、铁路罐车或公路罐车,应在所有方向上隔离800米(1/2英里);同时,考虑在所有方向上初始疏散800米(1/2英里)。(ERG, 2024)
  • Air and water reaction: 部分溶于水,密度小于水。
  • Hazard categories and classifications: STOT SE 3 (43.1%)
  • Non-human toxic extract: 无需外部活化,顺式和反式二氯二氨合铂(II)(DDP)以及顺式、反式(-)和反式(+)形式的二氯-1,2-二氨基环己基铂(II)(DDCP)和顺式、反式(-)、反式(+)-硫酸根-1,2-二氨基环己基铂(II)(SHP)对鼠伤寒沙门氏菌TA100和TA98表现出400倍的致突变性范围;它们对菌株TA100的致突变性比对菌株TA98高2-10倍。对于二氨基环己基络合物,致突变活性强烈依赖于络合物中二氨基环己基的立体异构体。对于菌株TA100,DDCP和SHP的反式(+)形式分别产生220和66回复物/纳摩尔,而顺式和反式(-)异构体诱导的回复物数量仅为反式(+)形式的10%和5%。
  • Non-fire leakage response: 消除所有点火源(禁止吸烟、火焰、火花或明火)于立即区域。除非穿戴适当的防护服,否则不要触摸损坏的容器或泄漏物质。如果可以在不冒险的情况下,停止泄漏。防止进入水道、下水道、地下室或密闭区域。用干土、沙子或其他不可燃材料吸收或覆盖并转移到容器中。不要让水进入容器。(ERG, 2024)
  • Personal protective equipment (PPE): 佩戴正压自给式呼吸器(SCBA)。在没有火灾风险时,佩戴制造商特别推荐的化学防护服。结构消防员的防护服提供热保护,但仅提供有限的化学保护。(ERG,2024)
  • Protective Action Standards (PAC): PAC-3: 140 [mg/m3]
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Research chemical CAS 694-83-7 99% 10L

Research chemical CAS 694-83-7 99% 10L, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

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