- Treatment： EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.
- Hazard summary： 豚鼠的皮肤研究表明严重刺激、良好吸收和致敏；在4周大鼠口服研究中观察到对甲状腺功能的影响（血清T4水平降低）；[EPA - PPRTV] 引起灼伤和流泪；可能引起皮肤和呼吸道致敏；吸入可能对上呼吸道和肺部造成腐蚀性损伤；食入有害；靶向肾脏和膀胱；[Sigma-Aldrich MSDS]
- exposure pathway： 吸入（L96）；口服（L96）；皮肤接触（L96）
- Harmful effect： 毒性肺炎 - 因吸入金属烟雾或有毒气体和蒸汽引起的肺部炎症。
- Toxicity summary： 氰化物是电子传递链第四复合物(存在于真核细胞的线粒体膜中)细胞色素c氧化酶的抑制剂。它与该酶中的三价铁原子结合。氰化物与这种细胞色素的结合阻止了电子从细胞色素c氧化酶向氧气的传递。结果，电子传递链被破坏，细胞无法再通过有氧呼吸产生ATP供能。主要依赖有氧呼吸的组织，如中枢神经系统和心脏，尤其受到影响。氰化物还通过与过氧化氢酶、谷胱甘肽过氧化物酶、高铁血红蛋白、羟基钴胺胺、磷酸酶、酪氨酸酶、抗坏血酸氧化酶、黄嘌呤氧化酶、琥珀酸脱氢...
- Regulatory information： 新西兰环境保护局化学品状态清单：苯基异硫氰酸酯：没有单独批准，但可在适当的团体标准下使用
- Toxicity Data： LD50: 87 mg/kg (口服, 小鼠) (L565) LD50: 250 mg/kg (皮下, 小鼠) (L565) LD50: 100 mg/kg (腹腔注射, 小鼠) (L565)
- Health Effects： 短时间内高浓度接触氰化物会损害大脑和心脏，甚至可能导致昏迷、癫痫、呼吸暂停、心脏骤停和死亡。慢性吸入氰化物会导致呼吸困难、胸痛、呕吐、血液变化、头痛和甲状腺肿大。皮肤接触氰化物盐会引起刺激并产生溃疡。(L96, L97)
- Symptoms and Signs： 氰化物中毒的特征是呼吸急促而深、呼吸困难、全身无力、头晕、头痛、眩晕、意识混乱、惊厥/癫痫发作，最终失去意识。(L96, L97)
- RAIS Toxicity Values： 口服亚慢性慢性参考剂量参考: PPRTV 当前
- Hazard categories and classifications： 水生慢性1 (24.3%)
- Carcinogen Classification： 对人类无致癌性迹象（未被IARC列出）。
- EPA Provisional Peer-Reviewed Toxicity Values： 证据权重(WOE)：信息不足，无法评估致癌潜力
- Hazard Quotient Level 3 or Cancer Risk Level 1E-04： 土壤饱和浓度 (mg/kg): 1.29e+02
- Hazard Quotient Level 0.1 or Cancer Risk Level 1E-06： 土壤饱和浓度 (mg/kg): 1.29e+02
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Research chemical CAS 103-72-0 ≥99% 25ml
Research chemical CAS 103-72-0 ≥99% 25ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
