- Harmful effect： 已有报道称苯肾上腺素和较少见的托吡卡胺可引起过敏性接触性皮炎，尽管防腐剂苯扎氯铵也可能是原因。检测致敏剂的方法包括皮肤斑贴试验和结膜激发试验。结膜激发试验被证明是安全且有用的。当皮肤斑贴试验呈阴性时，结膜激发试验可能检测出过敏。一项对37名使用散瞳眼药水后急性结膜炎患者的研究发现，93.5%的病例中苯肾上腺素是致敏剂，一名患者对防腐剂过敏。对苯肾上腺素的过敏反应在约3至4小时开始，在72小时内逐渐消退。管理措施包括避免或停止使用致敏剂...
- Toxicity summary： 使用地匹哌酮可以比等待托吡卡胺自行消退的时间缩短一半。不幸的是，FDA出于与安全性和有效性无关的原因将地匹哌酮撤出市场。目前，没有批准的方法可以逆转托吡卡胺引起的瞳孔放大，患者应佩戴太阳镜以减轻光敏感性。
- Hazard categories and classifications： 特定靶器官毒性-单次接触 3 (71%)
- Effects During Pregnancy and Lactation： 抗胆碱能药物可抑制动物的泌乳，显然是通过抑制生长激素和催乳素分泌。抗胆碱能药物也可降低非哺乳期妇女的血清催乳素。已建立泌乳的母亲体内的催乳素水平可能不会影响她母乳喂养的能力。
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Research chemical CAS 1508-75-4 1ml
Yuanye Research chemical CAS 1508-75-4 1ml, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.
