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Product introduction

WZB117是GLUT1的抑制剂，它可以抑制肺癌细胞A549和乳腺癌MCF7细胞的细胞增殖，IC50约为10 μM。应用 WZB117 是一种葡萄糖转运蛋白 1 (Glut1) 抑制剂，可下调糖酵解，诱导细胞周期停滞，并在体内外抑制癌细胞生长。 WZB-117 已被用于研究其在肿瘤干细胞中的肿瘤起始能力。也用于研究葡萄糖拮抗剂对 2-NBDG（2-（N-（7-硝基苯并-2-氧杂-1,3-二唑-4-基）氨基）-2-脱氧葡萄糖）摄取的影响。

Specs ⸢ View details ⸥

Chinese name

WZB 117

English name

WZB 117

Chinese alias

3-氟-1,2-亚苯基双(3-羟基苯甲酸酯) | 武智斌117

English alias

EX-A1492 | BCP24665 | BW167833 | [3-fluoro-2-(3-hydroxybenzoyl)oxyphenyl] 3-hydroxybenzoate | AC-32898 | 3-FLUORO-2-(3-HYDROXYBENZOYLOXY)PHENYL 3-HYDROXYBENZOATE | HY-19331 | WZB-117, >=98% (HPLC) | SCHEMBL19183300 | C71842 | s7927 | WZB117 | WZB-117 | 12

CAS number

1223397-11-2

molecular formula

C20H13FO6

molecular weight

368.31 g/mol

Exact mass

10mM in DMSO

PSA

93.100 Å²

Logp

4.1

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