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Product details

名称

XR8-89

英文名称

XR8-89

货号

X649775-5mg

包装规格

5mg

浓度

≥97%

储存温度

2-8°C储存,避光,干燥

运输条件

冰袋运输

产品介绍

XR8-89 is a potent papain-like protease (PL pro ) inhibitor with an IC 50 value of 0.1 μM. XR8-89 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. XR8-89 can be used for SARS-CoV-2 research In Vitro XR8-89 induces conformational changes manly in BL2 region and increases the activity against PL pro. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 0.1 μM (papain-like protease)

生化机理

XR8-89 是一种强效的木瓜蛋白酶（PL pro ）抑制剂，其 IC 50 值为 0.1 μM。XR8-89 可诱导 SARS-COV-2 木瓜蛋白酶发生构象变化，从而抑制 SARS-CoV-2 的复制。XR8-89 可用于 SARS-CoV-2 研究。

CAS号

2817811-16-6

分子式

C29H36N4O2S

分子量

504.69 g/mol

Smiles

CC1=CC=C(NC2CNC2)C=C1C(N[C@H](C)C3=CC=CC(C4=CC=C(S4)CN[C@@H]5C[C@H](O)CC5)=C3)=O

溶解性

DMSO : 50 mg/mL (99.07 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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