4′-Piperidinoacetophenone undergoes Claisen-Schmidt condensation with substituted benzaldehydes using NaOH-Al2O3 by microwave irradiation to give chalcones. It has antimycobacterial activity.4′-Piperidinoacetophenone was used as internal standard in the determination of pethidine, a narcotic analgesic drμg in body fluids by gas chromatography-tandem mass spectrometry. Pharmacological activity: Selective antimycobacterial activity Bronchodilator compound Modulation of flagellar motility in Chlamydomonas 4′-Piperidinoacetophenone undergoes Claisen-Schmidt condensation with substituted benzaldehydes using NaOH-Al2O3 by microwave irradiation to give chalcones. It has antimycobacterial activity. 4′-Piperidinoacetophenone was used as internal standard in the determination of pethidine, a narcotic analgesic drug in body fluids by gas chromatography-tandem mass spectrometry. Pharmacological activity: Selective antimycobacterial activity Bronchodilator compound Modulation of flagellar motility in Chlamydomonas